A radical prostatectomy is an operation to remove the prostate gland and some of the tissue around it. Radical prostatectomy is major surgery performed under general or regional anesthesia. This operation may be done by open surgery or by laparoscopic surgery through small incisions.

Two non-steroidal antiandrogens, designated MDV3100 and RD162, may be useful treatment for castration-resistant prostate cancer, Dr. Sawyers' team identified MDV3100 and RD162, diarylthiohydantoin compounds that remain active against the malignancy even in the face of elevated androgen receptor expression.

Testing in murine models of human castration-resistant prostate cancer, the authors found that RD162 and MDV3100 promoted tumor regression.
"While preliminary, these clinical data appear promising and validate the persistent role of androgen receptor in driving castration-resistant disease," the authors conclude.
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Hormonal therapy to lower testosterone levels
Two main types of medications are used for hormone therapy. You may need to take one or both types of these medications.
LHRH Agonists. This therapy uses medication to stop the testicles from making testosterone. Common examples of these drugs are leuprolide (Lupron®), goserelin (Zoladex®) and buserelin (Suprefact®). These medications are usually given
to you every 1 to 4 month by an injection into skin or muscle.
2. Antiandrogens
This therapy uses medication to block the action of testosterone. Common examples of these drugs are bicalutamide (Casodex®), flutamide (Euflex®), nilutamide (Anandron®) and cyproterone acetate (Androcur®). These medications are usually pills taken by mouth every day
info form www.cdha.nshealth.ca patient information

Donwload Hormone Therapy for Prostate Cancer

Ther is some Treatment Options For Prostate Cancer, consultation with your doctor which one treatmen options. Every options have side effect, treatment options for prostate cancer include :

1. Surgery.
2. External beam radiation therapy.
3. Prostate brachytherapy.
4. Hormone therapy.
5. Chemotherapy.
6. Cryosurgery.

Sometimes a combination of treatments is best for prostate cancer, such as surgery followed by external beam radiation.

Bob Leibowitz, M.D, Isaac Gorbaty, M.D, Mary Duong, P.A.-C
The package insert that accompanies any type of prescription for testosterone replacement products states that testosterone is “contraindicated in men with prostate cancer.” This means that you should never use any form of testosterone if you have prostate cancer. 99.9% plus of all physicians believe that if you give testosterone to a patient with prostate cancer, it’s “like adding gasoline to a fire.” We are taught that testosterone will markedly stimulate the growth of prostate cancer cells, cause widespread metastatic disease, and greatly hasten death. Testosterone replacement therapy has also been reported to cause permanent paralysis.
A number of years ago, I reviewed the medical literature regarding the relationship between testosterone and prostate cancer, especially in men who were previously treated for prostate cancer. I previously discussed this subject in detail in my September 2003 paper, “High-Dose Testosterone Replacement Therapy,” and the interested reader is directed to this paper.
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A radical prostatectomy is an operation to remove the prostate gland and some of the tissue around it. It is done to remove prostate cancer. This operation may be done by open surgery or by laparoscopic surgery through small incisions.
See Prostate Cancer radical Prostatectomy Video

Prostate cancer is the second most common cause of cancer death among men in the U.S. It was diagnosed in more than 180,000 men and claimed the lives of more than 28,000 men in the U.S. last year.
The novel agent, called abiraterone, shrank tumors by 30% or more in one-fourth of 31 patients whose prostate cancer continued to spread despite standard hormone therapy. In an additional 35% of men, tumors stopped growing.
The researchers also used PSA levels to evaluate abiraterone's effectiveness. PSA levels are a measure of a protein called prostate-specific antigen, which is produced by cells in the prostate. High PSA levels can signal cancer. The National Cancer Institute views a response to treatment as being seen when there is at least a 50% decline in PSA blood level.
After 12 weeks of treatment, abiraterone reduced PSA levels by 50% or more in 71% of the men. In two men, PSA fell to undetectable levels.
"This is currently the most promising prostate cancer drug on the horizon," says ASCO spokesman Howard Sandler, MD, chairman of radiation oncology at the Samuel Oschin Cancer Institute at Cedars-Sinai Medical Center in Los Angeles.
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